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Novel multicolor fluorescently labeled silica nanoparticles for interface fluorescence resonance energy transfer to and from labeled avidin

DOI to cite this document:
Saleh, Sayed M. ; Müller, Rainer ; Mader, Heike S. ; Dürkop, Axel ; Wolfbeis, Otto S.
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Date of publication of this fulltext: 18 Mar 2011 06:52


Fluorescent silica nanoparticles (SiNPs) were prepared by covalent attachment of fluorophores to the amino-modified surface of SiNPs with a typical diameter of 15 nm. The SiNPs are intended for use in novel kinds of fluorescence resonance energy transfer (FRET)-based affinity assays at the interface between nanoparticle and sample solution. Various labels were employed to obtain a complete set of ...


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