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In Vivo Phosphorescence Imaging of pO2 Using Planar Oxygen Sensors

Babilas, Philipp, Liebsch, Gregor, Schacht, Vivien, Klimant, Ingo, Wolfbeis, Otto S., Szeimies, Rolf-Markus and Abels, Christoph (2005) In Vivo Phosphorescence Imaging of pO2 Using Planar Oxygen Sensors. Microcirculation 12 (6), pp. 477-487.

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Objective: Oxygen-dependent quenching of luminescence of metal porphyrin complexes has been used to image the pO2 distribution over tumor and normal tissue. Methods: An experimental setup is described using a platinum(II)–octaethyl–porphyrin immobilized in a polystyrene matrix as transparent planar sensor. Results: Sensitivity over a broad range is high at low pO2 values (± 0.2 mm Hg at 0 mm Hg; ...


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Item type:Article
Date:September 2005
Institutions:Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Chemo- und Biosensorik (Prof. Antje J. Bäumner, formerly Prof. Wolfbeis)
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Keywords:dorsal skinfold chamber; intravital microscopy; microcirculation; oxygen; temperature
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Created at the University of Regensburg:Unknown
Item ID:20355
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