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The Epstein-Barr virus-encoded glycoprotein gp 110 (BALF 4) can serve as a target for antibody-dependent cell-mediated cytotoxicity (ADCC)

URN to cite this document:
urn:nbn:de:bvb:355-epub-203927
Jilg, Wolfgang ; Bogedain, C. ; Mairhofer, H. ; Gu, S. Y. ; Wolf, Hans J.
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Date of publication of this fulltext: 06 Apr 2011 07:56


Abstract

Antibody-dependent cell-mediated cytotoxicity (ADCC) is thought to play a major role in controlling the spread of the Epstein-Barr virus (EBV) in an infected individual. Recently, the viral membrane protein gp 350/220, which is also expressed at the surface of the virus producing cell, was identified as a target for ADCC reactions. Due to its glycoprotein nature, the EBV protein gp 110 is another ...

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