Reactivities of HIV-1 gag-derived peptides with antibodies of HIV-1-infected and uninfected humans

URN to cite this document:: urn:nbn:de:bvb:355-epub-204122
DOI to cite this document:: 10.5283/epub.20412

Haist, S. ; März, J. ; Wolf, Hans J. ; Modrow, Susanne

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Date of publication of this fulltext: 07 Apr 2011 06:42

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Abstract

A group of 41 peptides, each 24 amino acids long and overlapping with each other by 12 residues spanning the total gag open reading frame (orf) of HIV-1 (HTLV-IIIBH 10 isolate) were synthesized using Fmoc chemistry. The purified compounds were used in ELISA assays and tested for antibody reactivities in sera of human HIV-1-infected and noninfected individuals. Sera of HIV- humans showed ...