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The BI'LF4 trans-activator of Epstein-Barr virus is modulated by type and differentiation of the host cell

URN to cite this document:
urn:nbn:de:bvb:355-epub-204676
Marschall, M. ; Schwarzmann, F. ; Leser, U. ; Oker, B. ; Alliger, P. ; Mairhofer, H. ; Wolf, Hans J.
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Date of publication of this fulltext: 12 Apr 2011 07:54


Abstract

We have analyzed the activity and regulated expression of a new Epstein-Barr virus (EBV) trans-activator (I'ta) encoded by left reading frame 4 (BI'LF4) of the BamHI I'fragment. The gene was detected in all genomes of established EBV strains and individual isolates, with the exception of B95-8, where the type-specific deletion of this open reading frame is tolerated in vitro. Specific ...

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