Hepatitis B virus surface antigen as a reporter of promoter activity

URN to cite this document:: urn:nbn:de:bvb:355-epub-204882
DOI to cite this document:: 10.5283/epub.20488

Marschall, M. ; Motz, M. ; Leser, Ulrike ; Schwarzmann, F. ; Oker, B. ; Wolf, Hans J.

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Date of publication of this fulltext: 13 Apr 2011 09:14

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Abstract

The coding sequence for the hepatitis B virus surface antigen (HBsAg) was used as a new reporter gene for studies on eukaryotic promoter activity and upstream regulatory sequences. The data observed in transfection assays were comparable to results obtained with conventional chloramphenicol acetyltransferase (CAT) assays, as was demonstrated using various transcriptional regulation sequences. The ...