Identification of proteins encoded by Epstein-Barr virus trans-activator genes

URN to cite this document:: urn:nbn:de:bvb:355-epub-204923

Marschall, M. ; Leser, U. ; Seibl, R. ; Wolf, Hans J.

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Date of publication of this fulltext: 13 Apr 2011 08:56

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Abstract

Specific antisera were generated to characterize Epstein-Barr virus proteins reported to have trans-activating properties. Open reading frame BRLF1 was found to be expressed in two modifications in vivo, with molecular sizes ranging from 94 to 98 kilodaltons (kDa) depending on the cell line, whereas only one protein (Raji cells, 96 kDa) was detected by in vitro translation. Open reading frame ...