The antigenic index: a novel algorithm for predicting antigenic determinants

URN to cite this document:: urn:nbn:de:bvb:355-epub-205269
DOI to cite this document:: 10.5283/epub.20526

Jameson, B. A. ; Wolf, H.

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Date of publication of this fulltext: 15 Apr 2011 08:50

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Abstract

In this paper, we introduce a computer algorithm which can be used to predict the topological features of a protein directly from its primary amino acid sequence. The computer program generates values for surface accessibility parameters and combines these values with those obtained for regional backbone flexibility and predicted secondary structure. The output of this algorithm, the antigenic ...