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Zhu, X. X. ; Zeng, Y. ; Wolf, Hans J.

Detection of IgG and IgA antibodies to Epstein-Barr virus membrane antigen in sera from patients with nasopharyngeal carcinoma and from normal individuals

Zhu, X. X., Zeng, Y. and Wolf, Hans J. (1986) Detection of IgG and IgA antibodies to Epstein-Barr virus membrane antigen in sera from patients with nasopharyngeal carcinoma and from normal individuals. International journal of cancer. Journal international du cancer 37 (5), pp. 689-691.

Date of publication of this fulltext: 20 Apr 2011 12:44
Article
DOI to cite this document: 10.5283/epub.20554


Abstract

IgG and IgA antibodies to Epstein-Barr virus (EBV) membrane antigen (MA) were detected in sera from 96 NPC patients and normal individuals by the indirect immunofluorescence test. For MA/IgG antibody, 100% of NPC patients were positive with a GMT of 1:439.7 and 97.9% of normal individuals were positive with a GMT of 1:94.7. In contrast, for MA/IgA antibody, 58.3% of NPC patients were positive ...

IgG and IgA antibodies to Epstein-Barr virus (EBV) membrane antigen (MA) were detected in sera from 96 NPC patients and normal individuals by the indirect immunofluorescence test. For MA/IgG antibody, 100% of NPC patients were positive with a GMT of 1:439.7 and 97.9% of normal individuals were positive with a GMT of 1:94.7. In contrast, for MA/IgA antibody, 58.3% of NPC patients were positive with a GMT of 1:7.3 and none of the normal individuals were positive. There was no difference in the detection of antibodies to EBV MA when other P3HR-1 or B95-8 cell lines, differing in their major membrane antigen, were used.



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Details

Item typeArticle
Journal or Publication TitleInternational journal of cancer. Journal international du cancer
Publisher:Wiley-Liss
Volume:37
Number of Issue or Book Chapter:5
Page Range:pp. 689-691
Date1986
InstitutionsMedicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Identification Number
ValueType
3009331PubMed ID
10.1002/ijc.2910370508DOI
Classification
NotationType
Antibodies, Viral/analysisMESH
Antigens, Viral/immunologyMESH
Capsid ProteinsMESH
Carcinoma/immunologyMESH
Cell LineMESH
Fluorescent Antibody TechniqueMESH
Herpesvirus 4, Human/immunologyMESH
HumansMESH
Immunoglobulin A/analysisMESH
Immunoglobulin G/analysisMESH
Nasopharyngeal Neoplasms/immunologyMESH
Viral Matrix ProteinsMESH
Dewey Decimal Classification600 Technology > 610 Medical sciences Medicine
StatusPublished
RefereedUnknown
Created at the University of RegensburgUnknown
URN of the UB Regensburgurn:nbn:de:bvb:355-epub-205548
Item ID20554

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