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Human Cytomegalovirus IE1 Protein Elicits a Type II Interferon-Like Host Cell Response That Depends on Activated STAT1 but Not Interferon-γ

URN to cite this document:
urn:nbn:de:bvb:355-epub-205819
Knoblach, Theresa ; Grandel, Benedikt ; Seiler, Jana ; Nevels, Michael ; Paulus, Christina
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License: Creative Commons Attribution 3.0
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Date of publication of this fulltext: 19 Apr 2011 08:38


Abstract

Human cytomegalovirus (hCMV) is a highly prevalent pathogen that, upon primary infection, establishes life-long persistence in all infected individuals. Acute hCMV infections cause a variety of diseases in humans with developmental or acquired immune deficits. In addition, persistent hCMV infection may contribute to various chronic disease conditions even in immunologically normal people. The ...

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