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Expression of the Epstein-Barr virus major membrane proteins in Chinese hamster ovary cells

URN to cite this document:
urn:nbn:de:bvb:355-epub-205839
Motz, M. ; Deby, G. ; Jilg, Wolfgang ; Wolf, Hans J.
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Date of publication of this fulltext: 20 Apr 2011 12:39


Abstract

The gene of the major membrane antigen (gp250/350) of the Epstein-Barr virus (EBV) was isolated and inserted under the control of the SV40 early promoter into a eukaryotic expression vector, which allows selection for dhfr+ phenotype. Following transfection with this vector, Chinese hamster ovary cells express on their surfaces proteins immunologically similar to the major EBV membrane antigen. ...

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