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Strategies for the economic preparation of Epstein-Barr virus proteins of diagnostic and protective value by genetic engineering: a new approach based on segments of virus-encoded gene products

Wolf, Hans J. ; Motz, M. ; Kühbeck, R. ; Seibl, R. ; Jilg, Wolfgang ; Bayliss, G. J. ; Barrell, B. ; Golub, E. ; Zeng, Y. ; Gu, S. Y.



Abstract

Immunoprecipitation of Epstein-Barr viral proteins with various sera from normal adults, patients with fresh infectious mononucleosis or nasopharyngeal carcinoma was used to identify antigens which are of importance in the determination of immune status and characteristic of a particular disease. Some genes coding for of these antigens have been localized on the Epstein-Barr virus (EBV) genome by ...

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