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Wilmes, E. ; Wolf, Hans J. ; Haus, M.

Tonsillenkarzinome und Epstein-Barr-Virus ( = Tonsillar cancer and Epstein-Barr virus)

Wilmes, E., Wolf, Hans J. and Haus, M. (1983) Tonsillenkarzinome und Epstein-Barr-Virus ( = Tonsillar cancer and Epstein-Barr virus). Laryngologie, Rhinologie, Otologie 62 (12), pp. 586-589.

Date of publication of this fulltext: 06 May 2011 08:30
Article
DOI to cite this document: 10.5283/epub.20697


Abstract

Epstein-Barr Virus is an important aetiological factor in the development of nasopharyngeal carcinoma (NPC). Serology suggested that besides NPC some other tumours located within the lymphoepithelial ring of the throat (Waldeyer's ring) might be associated with EBV. Nucleic-acid hybridizations were carried out to detect the presence of EBV-DNA in tumour biopsies derived from tonsillar carcinomas. ...

Epstein-Barr Virus is an important aetiological factor in the development of nasopharyngeal carcinoma (NPC). Serology suggested that besides NPC some other tumours located within the lymphoepithelial ring of the throat (Waldeyer's ring) might be associated with EBV. Nucleic-acid hybridizations were carried out to detect the presence of EBV-DNA in tumour biopsies derived from tonsillar carcinomas. We were able to demonstrate the presence of EBV-DNA in the tumour cells of two poorly differentiated carcinomas. We think that only a small fraction of tonsillar carcinomas is positive for EBV. The aetiologic relationship of EBV with tumours of Waldeyer's ring is discussed.



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Details

Item typeArticle
Journal or Publication TitleLaryngologie, Rhinologie, Otologie
Publisher:Thieme
Volume:62
Number of Issue or Book Chapter:12
Page Range:pp. 586-589
Date1983
InstitutionsMedicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Identification Number
ValueType
6323895PubMed ID
10.1055/s-2007-1008503DOI
Classification
NotationType
AnimalsMESH
Antibodies, Viral/analysisMESH
Carcinoma, Squamous Cell/immunologyMESH
DNA, Viral/analysisMESH
Herpesvirus 4, Human/immunologyMESH
HumansMESH
Immunoglobulin A/analysisMESH
Nucleic Acid HybridizationMESH
Tonsillar Neoplasms/immunologyMESH
Tumor Virus Infections/etiologyMESH
Dewey Decimal Classification600 Technology > 610 Medical sciences Medicine
StatusPublished
RefereedUnknown
Created at the University of RegensburgUnknown
URN of the UB Regensburgurn:nbn:de:bvb:355-epub-206977
Item ID20697

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