An Epstein--Barr virus early protein induces cell fusion

URN to cite this document:: urn:nbn:de:bvb:355-epub-207084
DOI to cite this document:: 10.5283/epub.20708

Bayliss, G. J. ; Wolf, Hans J.

Preview

PDF
(1MB)

Date of publication of this fulltext: 03 May 2011 06:22

Alternative links to fulltext:Pubmed

Details

Preview

Export bibliographical data

Abstract

Superinfection of Raji cells with Epstein--Barr virus (EBV) leads to syncytium formation. Studies using metabolic inhibitors and amino acid analogues suggest that the fusion-inducing factor belongs to the early group of virus-specified proteins. Induction of early EBV protein synthesis in Raji cells by using various chemicals also leads to syncytium formation, indicating that the fusion process ...