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An Epstein--Barr virus early protein induces cell fusion

URN to cite this document:
urn:nbn:de:bvb:355-epub-207084
Bayliss, G. J. ; Wolf, Hans J.
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Date of publication of this fulltext: 03 May 2011 06:22


Abstract

Superinfection of Raji cells with Epstein--Barr virus (EBV) leads to syncytium formation. Studies using metabolic inhibitors and amino acid analogues suggest that the fusion-inducing factor belongs to the early group of virus-specified proteins. Induction of early EBV protein synthesis in Raji cells by using various chemicals also leads to syncytium formation, indicating that the fusion process ...

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