Attempts to detect virus-specific DNA sequences in human tumors. III. Epstein-Barr viral DNA in non-lymphoid nasopharyngeal carcinoma cells

URN to cite this document:: urn:nbn:de:bvb:355-epub-207728
DOI to cite this document:: 10.5283/epub.20772

Wolf, Hans J. ; zur Hausen, H. ; Klein, G. ; Becker, V. ; Henle, G. ; Henle, W.

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Date of publication of this fulltext: 05 May 2011 06:35

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Abstract

Fourteen tumors of the nasopharyngeal region were analyzed for the presence of Epstein-Barr virus-specific DNA by DNA-cRNA hybridization. These data were compared to the histology of the respective tumors and the seroreactivity of the tumor-bearing patient against EBV-related antigens. With one exception, all tumor pieces containing nasopharyngeal carcinoma cells hybridized significantly with ...