Wu, Meng, Lin, Zhihong, Mirsky, Vladimir and Wolfbeis, Otto S. (2001) Detection of DNA hybridization with surface plasmon resonance biosensor: comparison of immobilization of oligonucleotides by ssDNA and dsDNA. In: Zhou, Yikai, (ed.) Proceedings / International Conference on Sensor Technology (ISTC 2001): 10-12 October 2001, Wuhan, China. Proc. SPIE, 4414. SPIE, the International Society for Optical Engineering, Bellingham, Wash., pp. 23-26. ISBN 0-8194-4119-8.
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Abstract
In this research, a surface-plasmon resonance biosensor for nucleic acid detection was constructed, optimized and characterized. The kinetic response on hybridization was also studied. The biosensor was use as a platform for the study of the surface coverage control by single-strand or double-strand oligonucleotide immobilization. The dsDNA immobilization and offers a new way to surface coverage control for the nucleic acid biosensor construction.
Export bibliographical data
| Item type: | Book section | ||||
|---|---|---|---|---|---|
| Date: | 2001 | ||||
| Institutions: | Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Chemo- und Biosensorik (Prof. Antje J. Bäumner, formerly Prof. Wolfbeis) | ||||
| Identification Number: |
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| Dewey Decimal Classification: | 500 Science > 540 Chemistry & allied sciences | ||||
| Status: | Published | ||||
| Refereed: | Unknown | ||||
| Created at the University of Regensburg: | Unknown | ||||
| Item ID: | 21101 |
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