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The Skin: An Immunoreactive Target Organ during Interleukin-2 Administration

Dummer, R., Miller, K., Eilles, Christoph and Burg, G. (1991) The Skin: An Immunoreactive Target Organ during Interleukin-2 Administration. Dermatologica 183 (2), pp. 95-99.

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Six patients with metastatic malignant melanoma were treated systemically with dacarbazine and interleu-kin-2 (IL-2). During IL-2 administration all patients developed a macular erythematousrash followed by scaling which began 24–48 h after IL-2 infusion. The dermatological changes were associated with elevated interferon-γ and tumor necrosis factor α serum levels (immunoradiometric assay). ...


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Item type:Article
Institutions:Medicine > Abteilung für Nuklearmedizin
Identification Number:
DOI: 10.1159/000247645DOI
Keywords:Interleukin-2; Immunotherapy; Side effects; Interferon-γ: Tumor necrosis factor α
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Created at the University of Regensburg:Unknown
Item ID:21148
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