Induction of monokine production by tumor cells

URN to cite this document:: urn:nbn:de:bvb:355-epub-211796
DOI to cite this document:: 10.5283/epub.21179

Männel, Daniela N. ; Jänicke, R.

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Date of publication of this fulltext: 22 Jun 2011 08:17

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Abstract

Cells of the proerythromyeloid cell line K562 and of the T cell line Jurkat were able to induce an increase in TNF-, IL1 alpha-, and IL1 beta-mRNA expression in human peripheral blood derived monocytes in vitro. The activating principle of these tumor cells was associated with fractions of membrane preparations of distinct molecular mass, 32-38 kD for Jurkat cells and 46-54 kD for K562 cells, ...