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Discrimination of hepatocyte-stimulating activity from human recombinant tumor necrosis factor alpha

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Andus, T. ; Heinrich, P. C. ; Bauer, J. ; Tran-Thi, T. A. ; Decker, K. ; Männel, Daniela N. ; Northoff, H.
Date of publication of this fulltext: 22 Jun 2011 08:14


The involvement of tumor necrosis factor alpha (TNF alpha) in the regulation of acute-phase protein synthesis is currently under discussion. In this study the effect of human recombinant TNF alpha on the regulation of the 4 acute-phase proteins alpha 2-macroglobulin, albumin, alpha 1-proteinase inhibitor and alpha 1-acute-phase globulin was investigated in rat hepatocyte primary cultures. No ...


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