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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-211900
- DOI to cite this document:
- 10.5283/epub.21190
Alternative links to fulltext:Pubmed
Abstract
Tumor necrosis factor (TNF) has been determined as an endogenous mediator for endotoxin-induced tumor necrosis. This macrophage product has been biochemically characterized and its protein structure defined by molecular cloning of the TNF gene. Experiments with antibodies to TNF demonstrated that TNF acts as an effector molecule of activated cytotoxic macrophages involved in tumor destruction. ...

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