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Macrophages as a source of tumoricidal activity (tumor-necrotizing factor)

URN to cite this document:
urn:nbn:de:bvb:355-epub-212061
Männel, D.N. ; Moore, R. N. ; Mergenhagen, S. E.
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Date of publication of this fulltext: 22 Jun 2011 08:09


Abstract

Macrophage-enriched peritoneal exudate cells from mice infected with Mycobacterium bovis BCG, macrophage-like tumor cells (PU 5-1.8), and peritoneal macrophages propagated in vitro with macrophage growth factor released tumoricidal activity into the culture medium within 2 to 3 h after stimulation with nanogram quantities of bacterial lipopolysaccharide. The cytotoxic activities from each of the ...

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