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Generation and characterization of a lipopolysaccharide-induced and serum-derived cytotoxic factor for tumor cells

URN to cite this document:
urn:nbn:de:bvb:355-epub-212073
Männel, Daniela N. ; Meltzer, M. S. ; Mergenhagen, S. E.
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Date of publication of this fulltext: 22 Jun 2011 08:08


Abstract

Serum from Mycobacterium bovis BCG-infected mice treated with lipopolysaccharide was cytotoxic to tumor cells in vitro. Serum-induced cytotoxicity was estimated by measuring release of [3H]thymidine into culture supernatants of prelabeled tumor target cells. Serum from BCG-infected mice not treated with lipopolysaccharide or from uninfected mice treated with lipopolysaccharide was inactive. ...

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