Generation and characterization of a lipopolysaccharide-induced and serum-derived cytotoxic factor for tumor cells

URN to cite this document:: urn:nbn:de:bvb:355-epub-212073
DOI to cite this document:: 10.5283/epub.21207

Männel, Daniela N. ; Meltzer, M. S. ; Mergenhagen, S. E.

Preview

PDF
(1MB)

Date of publication of this fulltext: 22 Jun 2011 08:08

Alternative links to fulltext:Pubmed

Details

Preview

Export bibliographical data

Abstract

Serum from Mycobacterium bovis BCG-infected mice treated with lipopolysaccharide was cytotoxic to tumor cells in vitro. Serum-induced cytotoxicity was estimated by measuring release of [3H]thymidine into culture supernatants of prelabeled tumor target cells. Serum from BCG-infected mice not treated with lipopolysaccharide or from uninfected mice treated with lipopolysaccharide was inactive. ...