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Localization of gentamicin uptake in the acutely isolated inner ear of the rat

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Schmid, Katharina ; Strutz, Jürgen ; Gleich, Otto ; Kwok, Pingling
License: Creative Commons Attribution Non-commercial 3.0
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Date of publication of this fulltext: 18 Jul 2011 09:44


The quantitative analysis of fluorescence in frozen sections of rat inner ears exposed to Texas Red conjugated gentamicin revealed distinct gradients of gentamicin fluorescence. At 500 µg/ml gentamicin fluorescence occurred in inner and outer hair cells, the interdental cell region, the spiral limbus below the interdental cells, the nerve fiber bundle in the spiral lamina, the inner sulcus cells ...


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