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Are hypotension and rash after atracurium really caused by histamine release?

Doenicke, A., Moss, J., Lorenz, Wilfried, Hoernecke, R. and Gottardis, M. (1994) Are hypotension and rash after atracurium really caused by histamine release? Anesthesia and analgesia 78 (5), pp. 967-972.

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Abstract

A prospective, randomized, double-blind study was performed in 40 patients (ASA class I-III) treated with atracurium to ascertain whether histamine release caused hemodynamic or cutaneous changes. The treated group of 20 patients was premedicated with the H1 antagonist dimetindene (0.2 mg/kg) and the H2 antagonist ranitidine (1.25 mg/kg); the control group of 20 patients received saline. Six ...

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Item type:Article
Date:1994
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Tumorzentrum e.V.
Identification Number:
ValueType
7512805PubMed ID
Classification:
NotationType
AdolescentMESH
AdultMESH
AgedMESH
Atracurium/adverse effectsMESH
Double-Blind MethodMESH
Drug Eruptions/etiologyMESH
Histamine Release/physiologyMESH
HumansMESH
Hypotension/chemically inducedMESH
MaleMESH
Middle AgedMESH
Prospective StudiesMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:21738
Owner only: item control page

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