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Histamine release after injection of benzodiazepines and of etomidate. A problem associated with the solvent propylene glycol (= Libération d'histamine après injection de benzodiazépines et d'étomidate. Rôle du solvant propylène-glycol)

Doenicke, A., Lorenz, Wilfried, Hoernecke, R., Nebauer, A. E. and Mayer, M. (1993) Histamine release after injection of benzodiazepines and of etomidate. A problem associated with the solvent propylene glycol (= Libération d'histamine après injection de benzodiazépines et d'étomidate. Rôle du solvant propylène-glycol). Annales françaises d'anesthèsie et de rèanimation 12 (2), pp. 166-168.

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Abstract

Many drugs, especially when given in rapid sequence can cause histamine release. Ten healthy volunteers were premedicated with diazepam 10 mg.70 kg-1 i.v. and lormetazepam 1 mg.70 kg-1 i.v., respectively, 30 min prior to etomidate 0.15 mg.kg-1 i.v. in a single-blind, crossover study. The benzodiazepine lormetazepam and the hypnotic etomidate caused distinct increases in histamine plasma levels in ...

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Item type:Article
Date:1993
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Tumorzentrum e.V.
Identification Number:
ValueType
7690203PubMed ID
10.1016/S0750-7658(05)81025-1DOI
Classification:
NotationType
AdultMESH
Anti-Anxiety Agents/pharmacologyMESH
BenzodiazepinesMESH
Blood Pressure/drug effectsMESH
Etomidate/pharmacologyMESH
Heart Rate/drug effectsMESH
Histamine/bloodMESH
Histamine Release/drug effectsMESH
HumansMESH
Osmolar ConcentrationMESH
Propylene Glycols/adverse effectsMESH
Solvents/adverse effectsMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:21755
Owner only: item control page

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