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Sample taking problems in measuring actual histamine levels of human gastroduodenal mucosa: specific and general relevance in clinical trials on peptic ulcer pathogenesis and selective proximal vagotomy

Thon, K. P., Lorenz, Wilfried, Ohmann, C., Weber, D., Rohde, H. and Röher, H. D. (1985) Sample taking problems in measuring actual histamine levels of human gastroduodenal mucosa: specific and general relevance in clinical trials on peptic ulcer pathogenesis and selective proximal vagotomy. Gut 26 (11), pp. 1165-1178.

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Date of publication of this fulltext: 18 Aug 2011 13:01

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Abstract

Changes in histamine storage in the oxyntic mucosa of duodenal ulcer patients and their reversal by vagotomy and the histamine H2-antagonist cimetidine supported the hypothesis that histamine could be a causal factor in peptic ulcer pathogenesis. The specificity of these findings was impaired by problems in biopsy taking, however, and in the preparative steps before measuring the actual histamine ...

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Item type:Article
Date:1985
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Tumorzentrum e.V.
Identification Number:
ValueType
13369160PubMed ID
Classification:
NotationType
AdultMESH
AgedMESH
Biopsy/methodsMESH
Clinical Trials as TopicMESH
Cold TemperatureMESH
FemaleMESH
Gastric Mucosa/pathologyMESH
Histamine/metabolismMESH
HumansMESH
Intestinal Mucosa/pathologyMESH
MaleMESH
Middle AgedMESH
Peptic Ulcer/pathologyMESH
Specimen Handling/methodsMESH
Vagotomy, Proximal GastricMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:21799
Owner only: item control page

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