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Modulation of histamine release by fatty acids. A new in vitro model investigating adverse drug reactions in various species

Ennis, M. and Lorenz, Wilfried (1985) Modulation of histamine release by fatty acids. A new in vitro model investigating adverse drug reactions in various species. Annales françaises d'anesthèsie et de rèanimation 4 (2), pp. 124-128.

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Abstract

Histamine release caused by drugs and/or their solvents is a well known phenomenon. In this study, both in vivo (anaesthetized and conscious dogs) and in vitro (isolated rat peritoneal, human and guinea-pig lung mast cells) models were used. Cremophor E1 and six derivatives of 12-hydroxystearic acid were compared for their histamine releasing abilities. Although the three types of isolated mast ...

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Item type:Article
Date:1985
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Tumorzentrum e.V.
Identification Number:
ValueType
2408508PubMed ID
10.1016/S0750-7658(85)80185-4DOI
Classification:
NotationType
Alfaxalone Alfadolone Mixture/toxicityMESH
Anesthetics/toxicityMESH
AnimalsMESH
DogsMESH
Fatty Acids/pharmacologyMESH
FemaleMESH
Glycerol/toxicityMESH
Guinea PigsMESH
Histamine/bloodMESH
Histamine Release/drug effectsMESH
HumansMESH
MaleMESH
Mast Cells/secretionMESH
Propanidid/toxicityMESH
RatsMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:21803
Owner only: item control page

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