Go to content
UR Home

Modulation of histamine release by fatty acids. A new in vitro model investigating adverse drug reactions in various species

URN to cite this document:
urn:nbn:de:bvb:355-epub-218039
DOI to cite this document:
10.5283/epub.21803
Ennis, M. ; Lorenz, Wilfried
[img]
Preview
PDF
(430kB)
Date of publication of this fulltext: 19 Aug 2011 11:27


Abstract

Histamine release caused by drugs and/or their solvents is a well known phenomenon. In this study, both in vivo (anaesthetized and conscious dogs) and in vitro (isolated rat peritoneal, human and guinea-pig lung mast cells) models were used. Cremophor E1 and six derivatives of 12-hydroxystearic acid were compared for their histamine releasing abilities. Although the three types of isolated mast ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons