Go to content
UR Home

Modulation of histamine release by fatty acids. A new in vitro model investigating adverse drug reactions in various species

URN to cite this document:
DOI to cite this document:
Ennis, M. ; Lorenz, Wilfried
Date of publication of this fulltext: 19 Aug 2011 11:27


Histamine release caused by drugs and/or their solvents is a well known phenomenon. In this study, both in vivo (anaesthetized and conscious dogs) and in vitro (isolated rat peritoneal, human and guinea-pig lung mast cells) models were used. Cremophor E1 and six derivatives of 12-hydroxystearic acid were compared for their histamine releasing abilities. Although the three types of isolated mast ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons