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Effects of propofol ('Diprivan') on histamine release, immunoglobulin levels and activation of complement in healthy volunteers

Doenicke, A., Lorenz, Wilfried, Stanworth, D., Duka, T. and Glen, J. B. (1985) Effects of propofol ('Diprivan') on histamine release, immunoglobulin levels and activation of complement in healthy volunteers. Postgraduate medical journal 61 (Suppl3), pp. 15-20.

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Abstract

This randomized study compared the effects of the emulsion formulation of propofol with those of the Cremophor-containing agent Althesin. Plasma histamine concentration, immunoglobulin levels, total complement C3 and complement C3 conversion were measured prior to and following induction of anaesthesia in 32 male volunteers with either 2 mg/kg propofol or 0.05 ml/kg Althesin. In only one ...

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Item type:Article
Date:1985
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Tumorzentrum e.V.
Identification Number:
ValueType
3877283PubMed ID
Classification:
NotationType
AdolescentMESH
AdultMESH
Alfaxalone Alfadolone Mixture/pharmacologyMESH
Anesthesia, IntravenousMESH
Complement Activation/drug effectsMESH
Complement C3/analysisMESH
Histamine/bloodMESH
HumansMESH
Immunoglobulins/analysisMESH
MaleMESH
Phenols/pharmacologyMESH
PropofolMESH
Random AllocationMESH
Time FactorsMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:21826
Owner only: item control page
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