Histamine release in anaesthesia and surgery. premedication with H1- and H2-receptor antagonists: indications, benefits and possible problems

URN to cite this document:: urn:nbn:de:bvb:355-epub-218624
DOI to cite this document:: 10.5283/epub.21862

Doenicke, A. ; Lorenz, Wilfried

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Date of publication of this fulltext: 22 Aug 2011 14:06

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Abstract

Our clinical and experimental studies have so far demonstrated, that the drugs used in anaesthesia; such as hypnotics, sedatives, narcotics or muscle relaxants, release histamine. The intravenous short acting anaesthetic etomidate has not shown either in experimental studies or in clinical use for 10 years any anaphylactoid reaction. The benzodiazepines are another group of drugs which appear not ...