URN zum Zitieren dieses Dokuments: urn:nbn:de:bvb:355-epub-220384
Kohler, S. M. und Krämer, Bernhard K.
(1994)
Current therapeutic management of diabetic nephropathy.
Acta diabetologica 31 (3), S. 119-125.
Zum PubMed-Eintrag dieses Artikels
Zusammenfassung
Roughly 40% of all patients with insulin-dependent diabetes mellitus (IDDM) develop diabetic nephropathy with proteinuria, hypertension and a decrease in glomerular filtration rate 10 to 20 years after the onset of the disease, and 5 years later most patients suffer from end-stage renal disease. Microalbuminuria, defined as an urinary albumin excretion rate (UAER) between 30 and 300 mg/day, ...
Zusammenfassung
Roughly 40% of all patients with insulin-dependent diabetes mellitus (IDDM) develop diabetic nephropathy with proteinuria, hypertension and a decrease in glomerular filtration rate 10 to 20 years after the onset of the disease, and 5 years later most patients suffer from end-stage renal disease. Microalbuminuria, defined as an urinary albumin excretion rate (UAER) between 30 and 300 mg/day, strongly predicts the development of nephropathy in IDDM. Nearly all patients with IDDM, a decreasing glomerular filtration rate and a UAER > 300 mg/day have coexisting hypertensive disease additionally worsening renal function. We review the results of recent long-term studies of the current therapeutic management in diabetic patients by means of better blood pressure control, low-protein diet and near-normal blood glucose control in the early microalbuminuric phase as well as in the later phases of the disease characterized by diabetic nephropathy with a UAER > 300 mg/day. Since the large majority of studies have been performed on IDDM, our conclusions with regard to therapy are only valid in this subgroup of diabetic patients.
Bibliographische Daten exportieren
| Dokumentenart: | Artikel |
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| Datum: | 1994 |
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| Institutionen: | Nicht ausgewählt |
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| Identifikationsnummer: | |
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| Klassifikation: | | Notation | Art |
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| Albuminuria | MESH | | Antihypertensive Agents/therapeutic use | MESH | | Blood Glucose/metabolism | MESH | | Blood Pressure | MESH | | Diabetes Mellitus, Type 1/therapy | MESH | | Diabetic Angiopathies/physiopathology | MESH | | Diabetic Nephropathies/therapy | MESH | | Diet, Protein-Restricted | MESH | | Glomerular Filtration Rate | MESH | | Hemoglobin A, Glycosylated/analysis | MESH | | Humans | MESH | | Hypertension/physiopathology | MESH | | Prognosis | MESH |
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| Dewey-Dezimal-Klassifikation: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin |
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| Status: | Veröffentlicht |
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| Begutachtet: | Ja, diese Version wurde begutachtet |
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| An der Universität Regensburg entstanden: | Unbekannt / Keine Angabe |
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| Eingebracht am: | 07 Sep 2011 08:18 |
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| Zuletzt geändert: | 03 Jun 2018 02:27 |
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| Dokumenten-ID: | 22038 |
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