Krämer, Bernhard K., Pickert, A., Hohmann, C., Liebich, H. M., Müller, G. A., Hablitzel, M. and Risler, T.
(1992)
In vivo clearance and elimination of nine marker substances during hemofiltration with different membranes.
The International journal of artificial organs 15 (7), pp. 408-412.
Date of publication of this fulltext: 09 Sep 2011 09:08at PubMed
Abstract
The handling of low, middle and high molecular weight markers was examined in seven stable dialysis patients during hemofiltration with different membranes. Four membranes were examined in a randomized, crossover order (polysulfone, polyamide, AN69 polyacrylonitrile, Asahi polyacrylonitrile) by measuring plasma and dialysate concentrations of phosphate, creatinine, vitamin B12, beta ...
Abstract
The handling of low, middle and high molecular weight markers was examined in seven stable dialysis patients during hemofiltration with different membranes. Four membranes were examined in a randomized, crossover order (polysulfone, polyamide, AN69 polyacrylonitrile, Asahi polyacrylonitrile) by measuring plasma and dialysate concentrations of phosphate, creatinine, vitamin B12, beta 2-microglobulin, furanic acid, hippuric acid, retinol-binding protein, alpha-1-antitrypsin, and albumin. Sieving coefficients and plasma clearances of beta 2-microglobulin or retinol-binding protein were markedly or slightly lower during hemofiltration with the Asahi polyacrylonitrile membrane than with the other membranes (highest removal with polysulfone/AN69 polyacrylonitrile membranes). No differences of obvious clinical relevance could be seen between the four membranes. A high beta 2-microglobulin removal rate might be important to prevent dialysis-associated amyloidosis.
Export bibliographical data
| Item type: | Article |
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| Date: | 1992 |
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| Institutions: | UNSPECIFIED |
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| Identification Number: | | Value | Type |
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| 1516991 | PubMed ID |
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| Classification: | | Notation | Type |
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| Aged | MESH | | Creatinine/blood | MESH | | Dialysis Solutions/chemistry | MESH | | Hemofiltration | MESH | | Hippurates/blood | MESH | | Humans | MESH | | Kidney Failure, Chronic/therapy | MESH | | Membranes, Artificial | MESH | | Middle Aged | MESH | | Molecular Weight | MESH | | Phosphates/blood | MESH | | Random Allocation | MESH | | Renal Dialysis | MESH | | Retinol-Binding Proteins/analysis | MESH | | Retinol-Binding Proteins, Plasma | MESH | | Serum Albumin/analysis | MESH | | Vitamin B 12/blood | MESH | | beta 2-Microglobulin/analysis | MESH |
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| Dewey Decimal Classification: | 600 Technology > 610 Medical sciences Medicine |
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| Status: | Published |
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| Refereed: | Yes, this version has been refereed |
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| Created at the University of Regensburg: | Unknown |
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| Item ID: | 22047 |
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