Endothelins. Myocardial actions of a new class of cytokines

URN to cite this document:: urn:nbn:de:bvb:355-epub-220506

Krämer, Bernhard K. ; Nishida, M. ; Kelly, R. A. ; Smith, T. W.

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Date of publication of this fulltext: 09 Sep 2011 09:00

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Abstract

There is growing evidence to support the existence of a dynamic interaction in vivo between cardiac myocytes and adjacent microvascular endothelial cells in the regulation of both cardiac myocyte and possibly endothelial cell phenotype and function. Endothelins may be only one of several endogenous cytokines or autocoids that are released by the cardiac microvascular and/or endocardial ...