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Pharmacokinetic and blood pressure effects of carvedilol in patients with chronic renal failure

Krämer, Bernhard K., Ress, K. M., Erley, C. M. and Risler, T. (1992) Pharmacokinetic and blood pressure effects of carvedilol in patients with chronic renal failure. European journal of clinical pharmacology 43 (1), pp. 85-88.

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Abstract

The pharmacokinetic and acute systemic haemodynamic effects of a single oral dose of 50 mg carvedilol has been studied in 24 hypertensive patients with chronic renal failure. The patients were stratified into 3 groups according to the creatinine clearance: I 51-90 ml.min-1; II 26-50 ml.min-1; III 4-25 ml.min-1. The area under plasma level time curve AUC, the elimination half-life t1/2, the ...

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Item type:Article
Date:1992
Institutions:UNSPECIFIED
Identification Number:
ValueType
1505616PubMed ID
Classification:
NotationType
Administration, OralMESH
Antihypertensive Agents/pharmacokineticsMESH
Blood Pressure/drug effectsMESH
Carbazoles/pharmacokineticsMESH
FemaleMESH
HumansMESH
Hypertension/physiopathologyMESH
Kidney Failure, Chronic/physiopathologyMESH
MaleMESH
Metabolic Clearance RateMESH
Propanolamines/pharmacokineticsMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:22051
Owner only: item control page

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