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Simplified, rapid and inexpensive extraction procedure for a high-performance liquid chromatographic method for determination of disopyramide and its main metabolite mono-N-dealkylated disopyramide in serum

Mayer, F., Krämer, Bernhard K., Ress, K. M., Kühlkamp, V., Liebich, H. M., Risler, T. and Seipel, L. (1991) Simplified, rapid and inexpensive extraction procedure for a high-performance liquid chromatographic method for determination of disopyramide and its main metabolite mono-N-dealkylated disopyramide in serum. Journal of chromatography B 572 (1-2), pp. 339-345.

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Abstract

A simplified, rapid and inexpensive extraction procedure for the determination of the antiarrhythmic drug disopyramide and its main metabolite mono-N-desalkylated disopyramide in serum by high-performance liquid chromatography has been developed. The analysis uses ultraviolet detection at 254 nm, and a 5 micron reversed-phase column with a mobile phase of water-triethylamine-acetonitrile-PIC-B8 ...

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Item type:Article
Date:1991
Institutions:UNSPECIFIED
Identification Number:
ValueType
1818071PubMed ID
Classification:
NotationType
Chromatography, High Pressure LiquidMESH
Disopyramide/bloodMESH
HumansMESH
Reproducibility of ResultsMESH
Spectrophotometry, UltravioletMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:22053
Owner only: item control page

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