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Stromal upregulation of lateral epithelial adhesions: gene expression analysis of signalling pathways in prostate epithelium

URN to cite this document:
urn:nbn:de:bvb:355-epub-221405
DOI to cite this document:
10.5283/epub.22140
Chambers, Karen F. ; Pearson, Joanna F. ; Pellacani, Davide ; Aziz, Naveed ; Gužvić, Miodrag ; Klein, Christoph A. ; Lang, Shona H.
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Date of publication of this fulltext: 26 Sep 2011 09:36


Abstract

In 3D prostate cultures, stromal cells increase lateral epithelial cell adhesions. We show that this morphological effect is associated with gene expression changes to TGF beta signalling, cytoskeleton and anion activity.


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