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Prescont: Predicting protein-protein interfaces utilizing four residue properties

Zellner, H. ; Staudigel, M. ; Trenner, T. ; Bittkowski, M. ; Wolowski, V. ; Icking, C. ; Merkl, Rainer



Abstract

An important task of computational biology is to identify those parts of a polypeptide chain, which are involved in interactions with other proteins. For this purpose, we have developed the program PresCont, which predicts in a robust manner amino acids that constitute protein-protein interfaces (PPIs). PresCont reaches state-of-the-art classification quality on the basis of only four residue ...

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