Polysaccharide aus Nerium oleander: Struktur und biologische Aktivität [Polysaccharides from Nerium oleander: structure and biological activity]

Müller, B. M., Rosskopf, F., Paper, D. H., Kraus, J. and Franz, Gerhard (1991) Polysaccharide aus Nerium oleander: Struktur und biologische Aktivität [Polysaccharides from Nerium oleander: structure and biological activity]. Die Pharmazie 46 (9), pp. 657-663.

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Abstract

A water extraction of crushed leaves of Nerium oleander yielded 2.3% of a crude polysaccharide. The main fraction (67%) represents a pectic polysaccharide mainly composed of galacturonic acid besides rhamnose, arabinose and galactose. The polysaccharide structure was characterized by NMR, mild acid- and pectinase treatment combined with GC-MS analyses. In vivo tests for a possible antitumor ...

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Item type:

Article

Date:

1991

Institutions:

Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Franz

Identification Number:

Value	Type
1798730	PubMed ID

Classification:

Notation	Type
Animals	MESH
Antineoplastic Agents, Phytogenic/pharmacology	MESH
Cell Survival/drug effects	MESH
Female	MESH
Hydrolysis	MESH
Immunologic Factors/pharmacology	MESH
Limulus Test	MESH
Lymphocytes/drug effects	MESH
Macrophages/drug effects	MESH
Magnetic Resonance Spectroscopy	MESH
Male	MESH
Methylation	MESH
Mice	MESH
Mice, Inbred C3H	MESH
Mitogens/pharmacology	MESH
Phagocytosis/drug effects	MESH
Plant Extracts/pharmacology	MESH
Plants, Medicinal/chemistry	MESH
Polysaccharides/pharmacology	MESH
Protease Inhibitors/pharmacology	MESH
Structure-Activity Relationship	MESH
Tumor Cells, Cultured/drug effects	MESH