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Synthesis and binding properties of guanidinium biscarboxylates

Späth, A., Gonschor, Janina and König, Burkhard (2011) Synthesis and binding properties of guanidinium biscarboxylates. Monatshefte für Chemie - Chemical Monthly (142), pp. 1289-1308.

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The ammonium ion binding site of the enzyme glutaminase HisF inspired us to design guanidinium biscarboxylates as potential self-organized ionophores in molecular recognition. The syntheses of the title compounds based on aliphatic and aromatic building blocks, along with a general method for the preparation of δ-aminoethoxyacetic acids, are presented in this work. Investigation of the binding ...


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Item type:Article
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Projects:GRK 640 Sensory photoreceptors in natural and artificial systems
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Keywords:Guanidinium , Unnatural amino acid, Recognition, Ligand, Pyrrole
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:22585
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