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Antitumor and Immunological Activity of a ß-(1.3/1.6) Glucan from Glomerella cingulata

Gomaa, K., Kraus, J., Roßkopf, F., Röper, H. and Franz, Gerhard (1992) Antitumor and Immunological Activity of a ß-(1.3/1.6) Glucan from Glomerella cingulata. Journal of cancer research and clinical oncology 118 (2), pp. 136-140.

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Abstract

The in vivo antitumour activity of a beta 1----3/1----6 glucan from the fungus Glomerella cingulata was investigated in vivo. The glucan exhibited a strong inhibition of tumour growth of the allogeneic Sarcoma-180 as well as the syngeneic DBA/2-MC.SC-1 fibrosarcoma with inhibition ratios up to 100%. Against the hormone sensitive Noble-Nb-R prostate carcinoma the glucan alone showed a moderate ...

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Item type:Article
Date:1992
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Franz
Identification Number:
ValueType
1735734PubMed ID
Classification:
NotationType
AnimalsMESH
Diethylstilbestrol/pharmacologyMESH
Drug Screening Assays, AntitumorMESH
Fibrosarcoma/drug therapyMESH
Glucans/pharmacologyMESH
Lymphocyte Activation/drug effectsMESH
Macrophage Activation/drug effectsMESH
MaleMESH
Mast-Cell Sarcoma/immunologyMESH
MethylcholanthreneMESH
MiceMESH
Mice, Inbred C3HMESH
Mice, Inbred DBAMESH
Prostatic Neoplasms/drug therapyMESH
RatsMESH
Sarcoma 180/drug therapyMESH
Sizofiran/pharmacologyMESH
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:22792
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