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Anticoagulant and antithrombotic actions of a semisynthetic beta-1,3-glucan sulfate

Alban, S., Jeske, W., Welzel, D., Franz, Gerhard and Fareed, J. (1995) Anticoagulant and antithrombotic actions of a semisynthetic beta-1,3-glucan sulfate. Thrombosis research 78 (3), pp. 201-210.

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Abstract

Sulfation of the natural polysaccharide curdlan results in anticoagulantly active beta-1,3-glucan sulfates whose activity depends on various structural parameters. In this study the anticoagulant and antithrombotic effects of one of these beta-1,3-glucan sulfates (GS) were compared with those of a porcine mucosal heparin. GS produced a concentration dependent anticoagulant effect in all the ...

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Item type:Article
Date:1995
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Franz
Identification Number:
ValueType
7631300PubMed ID
Classification:
NotationType
AnimalsMESH
Anticoagulants/pharmacologyMESH
Factor Xa/antagonists & inhibitorsMESH
Fibrinolytic Agents/therapeutic useMESH
Glucans/therapeutic useMESH
Heparin/pharmacologyMESH
Jugular VeinsMESH
MaleMESH
Partial Thromboplastin TimeMESH
Prothrombin TimeMESH
RabbitsMESH
RatsMESH
Rats, Sprague-DawleyMESH
SwineMESH
Thrombin/antagonists & inhibitorsMESH
Thrombosis/prevention & controlMESH
beta-GlucansMESH
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:22804
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