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Plasma levels of total and free tissue factor pathway inhibitor (TFPI) as individual pharmacological parameters of various heparins

Alban, S. and Gastpar, R. (2001) Plasma levels of total and free tissue factor pathway inhibitor (TFPI) as individual pharmacological parameters of various heparins. Thrombosis and haemostasis 85 (5), pp. 824-829.

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Abstract

The release of circulating tissue factor pathway inhibitor (TFPI) into plasma by heparins is thought to contribute to their overall antithrombotic activity. In the presented study in healthy volunteers, we measured the heparin-induced increase of circulating total and free TFPI antigen and the aXa- and aIIa activity after subcutaneous (s.c.) injection of 9000 aXa-U of four different heparins: ...

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Item type:Article
Date:2001
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Franz
Identification Number:
ValueType
11372675PubMed ID
Classification:
NotationType
AdolescentMESH
AdultMESH
Area Under CurveMESH
Enoxaparin/pharmacologyMESH
Factor Xa/antagonists & inhibitorsMESH
Heparin/pharmacologyMESH
Heparin, Low-Molecular-Weight/pharmacologyMESH
HumansMESH
KineticsMESH
Lipoproteins/drug effectsMESH
MaleMESH
Molecular WeightMESH
Prothrombin/antagonists & inhibitorsMESH
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:22823
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