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Transient methylation of dolichyl oligosaccharides is an obligatory step in halobacterial sulfated glycoprotein biosynthesis

URN to cite this document:
urn:nbn:de:bvb:355-epub-228865
Lechner, J. ; Wieland, F. ; Sumper, Manfred
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Date of publication of this fulltext: 08 Dec 2011 07:04


Abstract

Biosynthesis of sulfated saccharides that are linked to asparagine residues in the cell surface glycoprotein of Halobacterium halobium via a glucose residue involves sulfated dolichyl-monophosphoryl oligosaccharide intermediates (Lechner, J., Wieland, F., and Sumper, M. (1985) J. Biol. Chem. 260, 860-866). During isolation and characterization of these lipid oligosaccharides we detected a group ...

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