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Eplerenone prevents salt-induced vascular stiffness in Zucker diabetic fatty rats: a preliminary report

Resch, Markus, Schmid, Peter M., Amann, Kerstin, Fredersdorf, Sabine, Weil, Joachim, Schach, Christian, Birner, Christoph, Griese, Daniel P., Kreuzer, Peter M., Brunner, Sabine, Luchner, Andreas, Riegger, Günter A. J. and Endemann, Dierk H. (2011) Eplerenone prevents salt-induced vascular stiffness in Zucker diabetic fatty rats: a preliminary report. Cardiovascular diabetology 10, p. 94.

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Date of publication of this fulltext: 11 Apr 2012 09:12

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Abstract

Background Aldosterone levels are elevated in a rat model of type 2 diabetes mellitus, the Zucker Diabetic fatty rat (ZDF). Moreover blood pressure in ZDF rats is salt-sensitive. The aim of this study was to examine the effect of the aldosterone antagonist eplerenone on structural and mechanical properties of resistance arteries of ZDF-rats on normal and high-salt diet. Methods After the ...

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Item type:Article
Date:2011
Institutions:Medicine > Lehrstuhl für Innere Medizin II
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
22008236PubMed ID
10.1186/1475-2840-10-94DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:23727
Owner only: item control page

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