DX5+NKT cells display phenotypical and functional differences between spleen and liver as well as NK1.1-Balb/c and NK1.1+ C57Bl/6 mice.

URN to cite this document:: urn:nbn:de:bvb:355-epub-237865
DOI to cite this document:: 10.5283/epub.23786

Werner, Jens M.

; Busl, Elisabeth ; Farkas, Stefan A. ; Schlitt, Hans J. ; Geissler, Edward K. ; Hornung, Matthias

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Date of publication of this fulltext: 12 Apr 2012 11:10

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Abstract

Background: Natural killer T cells represent a linkage between innate and adaptive immunity. They are a heterogeneous population of specialized T lymphocytes composed of different subsets. DX5(+)NKT cells are characterized by expression of the NK cell marker DX5 in the context of CD3. However, little is known about the phenotype and functional capacity of this unique cell population. Therefore, ...