Modulation of TTX-sensitive voltage-dependent Na+ channels by beta-bungarotoxin in rat cerebellar neurons

URN to cite this document:: urn:nbn:de:bvb:355-epub-237911
DOI to cite this document:: 10.5283/epub.23791

Guo, Da ; Xiang, Wei ; Seebahn, Angela ; Becker, Cord-Michael ; Strauss, Olaf

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Date of publication of this fulltext: 12 Apr 2012 11:07

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Abstract

Background The modulation of voltage-dependent Na+ channels by lipid metabolites such as arachidonic acid or eicosanoids plays a role in physiological functions as well as in degenerative diseases. So far TTX-resistant channels were found mainly to be regulated by lipid metabolites. Results We investigated the lipid-dependent modulation of TTX-sensitive (TTX-s) Na+ channels using ...