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Chemiluminescence-based detection and comparison of protein amounts adsorbed on differently modified silica surfaces

Müller, Rainer ; Hiller, Karl-Anton ; Schmalz, Gottfried ; Ruhl, Stefan


The biol. consequences of protein adsorption on biomaterial surfaces are considered to be of utmost importance for their biocompatibility. A new method based on amino group-labeling coupled to a chemiluminescence reaction for direct detn. of proteins adsorbed on material surfaces was employed. This method was used to explore the effects of surface chem. and surface roughness on protein ...


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