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Influence of different collagen species on physico-chemical properties of crosslinked collagen matrices

Angele, Peter ; Abke, Jochen ; Kujat, R. ; Faltermeier, H. ; Schumann, Detlef ; Nerlich, Michael ; Kinner, B. ; Englert, Carsten ; Ruszczak, Z. ; Mehrl, R. ; Müller, Rainer



Abstract

Collagen-based scaffolds are appealing products for the repair of cartilage defects using tissue engineering strategies. The present study investigated the species-related differences of collagen scaffolds with and without 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide/N-hydroxysuccinimide-crosslinking. Resistance against collagenase digestion, swelling ratio, amino acid sequence, shrinkage ...

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