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Conversion of carbohydrates in low melting mixtures and Melanoma Inhibitory Activity (MIA) protein inhibitors for the treatment of malignant melanoma

Ruß, Carolin (2013) Conversion of carbohydrates in low melting mixtures and Melanoma Inhibitory Activity (MIA) protein inhibitors for the treatment of malignant melanoma. PhD, Universität Regensburg.

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Date of publication of this fulltext: 01 Jul 2013 13:35

Abstract (English)

In the course of this project, acidic, basic, metal, and photo catalysts were applied to carbohydrate melts. We aimed to find chemical reactions converting carbohydrates in a selective and efficient way into fine chemicals in this screening process. The present study revealed that under basic conditions carbohydrates isomerise via well-known keto-enediol intermediates which are in equilibrium. ...

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Translation of the abstract (German)

Im Verlauf dieses Projektes wurden Säure-, Basen-, Metall- und Photokatalysatoren hinsichtlich ihrer Wirkung auf Kohlenhydrat-Schmelzen untersucht. Unser Ziel war es in einem „Screening“-Verfahren chemische Reaktionen zu finden, in denen Kohlenhydrate, speziell Monosaccharide, selektiv und effizient zu Feinchemikalien umgesetzt werden. Unter Basen-, Metall- und Photokatalyse verliefen die ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:1 July 2013
Referee:Prof. Dr. Burkhard König
Date of exam:13 July 2012
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Keywords:renewable resources, sugar melts, glycosylurea, malignant melanoma, MIA protein, MIA inhibitors, drug delivery, PEGylation, PEG hydrogels
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:25370
Owner only: item control page

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