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Conversion of carbohydrates in low melting mixtures and Melanoma Inhibitory Activity (MIA) protein inhibitors for the treatment of malignant melanoma

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Ruß, Carolin
Date of publication of this fulltext: 01 Jul 2013 13:35

Abstract (English)

In the course of this project, acidic, basic, metal, and photo catalysts were applied to carbohydrate melts. We aimed to find chemical reactions converting carbohydrates in a selective and efficient way into fine chemicals in this screening process. The present study revealed that under basic conditions carbohydrates isomerise via well-known keto-enediol intermediates which are in equilibrium. ...


Translation of the abstract (German)

Im Verlauf dieses Projektes wurden Säure-, Basen-, Metall- und Photokatalysatoren hinsichtlich ihrer Wirkung auf Kohlenhydrat-Schmelzen untersucht. Unser Ziel war es in einem „Screening“-Verfahren chemische Reaktionen zu finden, in denen Kohlenhydrate, speziell Monosaccharide, selektiv und effizient zu Feinchemikalien umgesetzt werden. Unter Basen-, Metall- und Photokatalyse verliefen die ...


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