Go to content
UR Home

Untersuchung molekularer Therapie-Response-Marker bei lokal fortgeschrittenen Harnblasenkarzinomen mit adjuvanter Chemotherapie

Leicht, Christina (2012) Untersuchung molekularer Therapie-Response-Marker bei lokal fortgeschrittenen Harnblasenkarzinomen mit adjuvanter Chemotherapie. PhD, Universität Regensburg.

License: Publishing license for publications excluding print on demand
Download (1MB)
Date of publication of this fulltext: 16 Aug 2012 07:13

Abstract (German)

Grundlage dieser Arbeit war das Datenmaterial von 327 Patienten, welche alle an einem invasiven Harnblasenkarzinom erkrankt waren und eine adjuvante Chemotherapie erhalten hatten. Aus den paraffineingebetteten Tumorgewebeproben wurden sogenannte Tissue Microarrays hergestellt, welche im Anschluss immunhistochemisch untersucht worden sind. Es konnte nachgewiesen werden, dass ein signifikanter ...


Translation of the abstract (English)

Basis of this study was the data of 327 patients, which were diagnosed with invasive bladder cancer and received adjuvant chemotherapy. Tissue microarrays were constructed to study the immunohistochemical expression of Emmprin, p53, BAX, and BCL2. It was demonstrated that there is a significant correlation between positive lymph node status and survival. Also a blood vessel invasion of the tumor ...


Export bibliographical data

Item type:Thesis of the University of Regensburg (PhD)
Date:16 August 2012
Referee:Prof. Dr. Arndt Hartmann
Date of exam:31 July 2012
Institutions:Medicine > Lehrstuhl für Pathologie
Interdisciplinary Subject Network:Not selected
Keywords:Urothelkarzinom, Harnblasenkarzinom, Tissue-Mikroarray, Emmprin, molekulare Prognosemarker, Tumormarker, Prognose, adjuvante Chemotherapie, bladder cancer, tissue microarray, Emmprin, molecular markers, prognostic indicators, adjuvant chemotherapy
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:25555
Owner only: item control page


Downloads per month over past year

  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons