Go to content
UR Home

Increased myocardial SERCA expression in early type 2 diabetes mellitus is insulin dependent: In vivo and in vitro data

URN to cite this document:
urn:nbn:de:bvb:355-epub-258402
DOI to cite this document:
10.5283/epub.25840
Fredersdorf, Sabine ; Thumann, Christian ; Zimmermann, Wolfram H. ; Vetter, Roland ; Graf, Tobias ; Luchner, Andreas ; Riegger, Günter A. J. ; Schunkert, Heribert ; Eschenhagen, Thomas ; Weil, Joachim
[img]
Preview
License: Creative Commons: Attribution 3.0
PDF - Published Version
(267kB)
Date of publication of this fulltext: 07 Sep 2012 07:00



Abstract

Background: Calcium (Ca2+) handling proteins are known to play a pivotal role in the pathophysiology of cardiomyopathy. However little is known about early changes in the diabetic heart and the impact of insulin treatment (Ins). Methods: Zucker Diabetic Fatty rats treated with or without insulin (ZDF +/- Ins, n = 13) and lean littermates (controls, n = 7) were sacrificed at the age of 19 weeks. ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons